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Modeling TB-HIV syndemic and treatment

机译:模拟TB-HIV的同步和治疗

摘要

Tuberculosis (TB) and human immunodeficiency virus (HIV) can be considered adeadly human syndemic. In this article, we formulate a model for TB and HIVtransmission dynamics. The model considers both TB and acquired immunedeficiency syndrome (AIDS) treatment for individuals with only one of theinfectious diseases or both. The basic reproduction number and equilibriumpoints are determined and stability is analyzed. Through simulations, we showthat TB treatment for individuals with only TB infection reduces the number ofindividuals that become co-infected with TB and HIV/AIDS, and reduces thediseases (TB and AIDS) induced deaths. Analogously, the treatment ofindividuals with only AIDS also reduces the number of co-infected individuals.Further, TB-treatment for co-infected individuals in the active and latentstage of TB disease, implies a decrease of the number of individuals thatpasses from HIV-positive to AIDS.
机译:结核病(TB)和人类免疫缺陷病毒(HIV)可以被视为人类综合症。在本文中,我们为结核和HIV传播动态建立模型。该模型将结核病和获得性免疫缺陷综合症(AIDS)的治疗方法同时考虑到仅患有一种或两种传染病的患者。确定基本的繁殖数量和平衡点,并分析稳定性。通过模拟,我们表明,仅感染结核病的人进行结核病治疗可以减少与结核病和艾滋病毒/艾滋病共同感染的人数,并减少疾病(结核病和艾滋病)导致的死亡。类似地,仅爱滋病患者的治疗也减少了合并感染的人数。此外,对处于活跃和潜伏期结核病的合并感染者进行结核病治疗,意味着减少了艾滋病毒呈阳性的人的数量艾滋病。

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